Saturday, October 31, 2009

Bio-identical Hormones are only natural if they are Biomimetic–

Bio-identical Hormones are only natural if they are Biomimetic–

If you are debating hormone replacement therapy, you’re not alone. Women everywhere are looking for answers and when they can’t find them, they look to their healthcare providers and pharmacists for help. According to the US Census Bureau, there were an estimated 78.2 million baby boomers, as of July 1, 2005, and over 47 million of them are women experiencing discomfort from menstruation to menopause, to loss of libido and beyond.

For those who still do not use any Hormone Replacement Therapy (HRT), the idea of anti-aging and bio-identical hormones has become intriguing. A myriad of products on the market make the right choice difficult.

People have become accustomed to talking about bio-identical hormone replacement therapy (BHRT) in menopause and anti-aging medicines versus synthetic big pharmaceutical products like Prempro from Wyeth. Bio-identical hormone products are usually created from natural sources of plant hormones which match the chemical structure of hormones produced by the human body. The premise is that the body can’t distinguish created bio-identical hormones from the ones the female ovaries produce naturally. The term bio-identical has basically become a catch all phrase for anything that is not a synthetic hormone. However “bio-identical” hormones can only be truly accurately bio-identical if the hormones for replacement mimic, not only those found in the body, but mimic the natural biological process as well.

In other words, natural plant derived hormones can accurately be termed bio-identical only when they are dosed in a Biomimetic fashion; that would be in a rhythm. Biomimetic hormones, the scientifically accurate term, are derived from plant sources and mimic the natural undulating or wavelike rhythms of the hormone blood levels in a normal menstrual cycle in a healthy young woman. It is this natural rhythm that is missing from all other bio-identical and synthetic hormone replacement therapies. It is the absence of this natural rhythm, according to T.S. Wiley, the developer of the Wiley Protocol, that is responsible for the vast side-effects in both camps.

So what exactly is meant by “the rhythm”? The body has rhythms that are governed by a master clock that works much like a conductor. It strikes up one section of the body’s orchestra as another quiets down, taking its main cue from light signals in the environment to stay in sync with the 24-hour day. Our body’s hormones surge and ebb to this maestro’s baton, controlling all endocrine function, predominantly a woman’s health for reproduction.

It is the circadian clock in our cells that measures one 24 hour spin of the planet. For 28 days the moon adds its light to create the menstrual rhythm for the body. The Wiley Protocol uses these natural rhythms in nature to establish the proper doses of estradiol and natural progesterone that mimic the natural hormones which would be produced by your body if you were young. The topical creams and their amounts vary throughout the 28 day cycle to restore the hormone levels of youth because young women, for the most part, don’t have heart attacks, breast cancer, Alzheimer’s, osteoporosis, or type 2 diabetes.

Uncertainty about any HRT began when The National Institute of Health (NIH), sponsored the Women’s Health Initiative (WHI). This study of more than 161,000 women was designed to identify the benefits and risks of using hormone restoration therapy to prevent chronic diseases such as heart disease, breast cancer and osteoporosis in postmenopausal women. Many people, including doctors, did not realize that the results of WHI Study dealt with only women over 65 who were taking only synthetic hormone replacement therapy which consisted of the drugs PremPro and Premarin only. The study was ended mid-stream in 2002 when, WHI investigators found that the risks of this approach using synthetic therapy exceeded the safety limits established at the beginning of the study. They never looked at compounded bio-identical hormones in static doses because they are prescribed and dosed too many different ways.

Women deserve something proven to be safe and reliable. A new study, Bio-identical Hormones On Trial, or B.H.O.T., will soon begin at the College of Nursing and Health Sciences at the University of Texas, Tyler. The principal objective of the study will be to examine clinical outcomes and quality of life indicators of patients receiving BHRT at 10 to 12 primary care provider’s practices. This study will be the first of its kind to track and quantify outcomes based on dosing and patterns of administration of BHRT.

In 2030 there will be 57.8 million baby boomers living with many of the health issues that we may suffer between the ages of 66 and 84. There’s a chance that those who choose rhythmic replacement, the Wiley Protocol, could age to a healthier more graceful tune. Think about it

Tuesday, October 13, 2009

Read This if You are Worried About the Swine Flu!




P. O. Box 510518, Punta Gorda, FL 33951-0518

An international financial, economic, political and social commentary.

Published and Edited by: Bob Chapman

"Data gleaned indirectly from anonymous testimony of Navy wives of the affected crew via the internet radio show A Marine Disquisition as follows:

* 1. Unnamed US Navy vessel put to sea in April with 347 man crew.
* 2. Entire crew was vaccinated with H1N1 Swine Flu vaccine shortly after they put to sea.
* 3. Crew sickened so severely that other ships had to respond to render aid. 16 Medical Dr.s put aboard from an unnamed aircraft carrier and other responding vessels. Total of 50 Navy personnel sent aboard to respond to crisis.
* 4. Two of the crew of 347 died - including the Captain of the ship (a Lieutenant Commander) and a Chief Petty Officer.
* 5. 50 personnel sent aboard to help are quarantined in Navy hospital in Balboa, Spain after 10 of them caught the flu from the ship's crew. Two of the 50 quarantined are in serious condition at last report.
* 6. Of the 347 man crew that were vaccinated, 333 contracted the H1N1 flu FROM THE VACCINE. Two died, as mentioned above, and 331 survived. Only 14 of the 347 vaccinated sailors did not show any ill effects from the vaccine.
* 7. Navy has threatened all the spouses of the ship's crew to remain silent - claiming all this information is classified. Some are whistle-blowing and that is where this information is coming from.
* 8. On the unnamed aircraft carrier that provided assistance, 415 sailors contracted the swine flu and are currently quarantined onboard.

PLEASE pass this along. The truth is that the swine flu epidemic will be created BY THE VACCINE. If we don't take it, there will be no epidemic. From this one test it's apparent that the vaccine as tested on that ship's crew in April is 96% effective at infecting the recipient with swine flu. Such an infection rate is impossible to achieve by any natural means. Though it only killed 1% immediately, there is no telling what the long term effects on those injected with the vaccine will be. See the research on the long term effects of the 1976 swine flu vaccine, and the Gulf War anthrax vaccine programs for more information.
Also note that mere contact with those that have been vaccinated creates a 20% chance of you contracting the swine flu even if you have not been vaccinated. Please pass this data along to anyone you care about!"

Sunday, October 11, 2009

Health, Beauty, and Aging are my Favorite Subjects

For the past two years I have been interested in learning more about what makes us age and what can help us slow down the aging process. I became interested in this subject when I started to see changes in myself related to aging. Skin changes, hair changes, sleep and energy changes, body changes, etc. I started with researching the cause of these changes and I discovered it was hormone related and vitamin deficiency or loss of efficiency (depending on your perspective).

Yes, reaching a ripe old age on lots of pharmaceutical medications is what today's women are experiencing. Thanks to the Women's Health Initiative study done by Wyeth-Ayerst in 1998-2002 which showed us that synthetic oral estrogen and synthetic oral progestin are a bad way to replace hormones and lead to more heart disease, strokes, breast cancer, and dementia. We don't live in a "natural society" any more. We live in an artificial society of lights, electricity, and processed food! And yes, not being able to sleep, heart palpitations, depression, anxiety, constipation, gastritis, urinary tract infections, divorce, memory loss, muscle wasting, weight gain, decreased sense of well being are the result of a loss of our biological hormones and cell control which we define now as menopause. NO HORMONES do kill people SLOWLY AND AGONIZINGLY. The women I know in their 50's and 60's who haven't yet replaced their hormones don't feel very good.

What hasn't been discussed in mainstream media and standard of care medicine is how should we replace hormones? How come we aren't telling women and men that hormones need to be replaced the way our body functions; in ascending and descending doses of estradiol and progesterone (or testosterone) over a 28 day cycle that ends with a menstrual period if a uterus is intact and mimics serum levels of healthy young females and young healthy males. Maybe because no one can profit from keeping us healthy. Or because it can't be labeled and sold as a pharmaceutical drug?

What I do know is that we all have a choice. For more information visit my web site or google my name Gretchen Jones hormones to find out more information.

Call my office to set up an appointment or email me 815-476-5210 or

More about Vitamin D

This is straight from Wikipedia:

Role in cancer prevention and recovery

The vitamin D hormone, calcitriol, has been found to induce death of cancer cells in vitro and in vivo. The anti-cancer activity of vitamin D is thought to result from its role as a nuclear transcription factor that regulates cell growth, differentiation, apoptosis and a wide range of cellular mechanisms central to the development of cancer.[65] These effects may be mediated through vitamin D receptors expressed in cancer cells.[14]
A search of primary and review medical literature published between 1970 and 2007 found an increasing body of research supporting the hypothesis that the active form of vitamin D has significant, protective effects against the development of cancer. Epidemiological studies show an inverse association between sun exposure, serum levels of 25(OH)D, and intakes of vitamin D and risk of developing and/or surviving cancer. In 2005, scientists released a metastudy which demonstrated a beneficial correlation between vitamin D intake and prevention of cancer. Drawing from a meta-analysis of 63 published reports, the authors showed that intake of an additional 1,000 international units (IU) (or 25 micrograms) of vitamin D daily reduced an individual's colon cancer risk by 50%, and breast and ovarian cancer risks by 30%.[66][67][68] A scientific review undertaken by the National Cancer Institute found that vitamin D was beneficial in preventing colorectal cancer, which showed an inverse relationship with blood levels of 80 nmol/L or higher associated with a 72% risk reduction. However, the same study found no link between baseline vitamin D status and overall cancer mortality.[69]
A 2006 study using data on over 4 million cancer patients from 13 different countries showed a marked difference in cancer risk between countries classified as sunny and countries classified as less–sunny for a number of different cancers.[70] Research has also suggested that cancer patients who have surgery or treatment in the summer — and therefore make more endogenous vitamin D — have a better chance of surviving their cancer than those who undergo treatment in the winter when they are exposed to less sunlight.[71] Another 2006 study found that taking the U.S. RDA of vitamin D (400 IU per day) cut the risk of pancreatic cancer by 43% in a sample of more than 120,000 people from two long-term health surveys.[72][73] A randomized intervention study involving 1,200 women, published in June 2007, reports that vitamin D supplementation (1,100 international units (IU)/day) resulted in a 60% reduction in cancer incidence, during a four-year clinical trial, rising to a 77% reduction for cancers diagnosed after the first year (and therefore excluding those cancers more likely to have originated prior to the vitamin D intervention).[74][75] Research has also indicated beneficial effects of high levels of calcitriol on patients with advanced prostate cancer.[76]
Low levels of vitamin D in serum have also been correlated with breast cancer disease progression and bone metastases,[77] and studies suggest that increased intake of vitamin D reduces the risk of breast cancer in premenopausal women.[78] Polymorphisms of the vitamin D receptor (VDR) gene have been associated with an increased risk of breast cancer.[77] Impairment of the VDR-mediated gene expression is thought to alter mammary gland development or function and may predispose cells to malignant transformation. Women with homozygous FOK1 mutations in the VDR gene had an increased risk of breast cancer compared with the women who did not. FOK1 mutation has also been associated with decreasing bone mineral density which in turn may be associated with an increase in the risk of breast cancer.[79]
[edit]Role in cardiovascular disease prevention

Research indicates that vitamin D may play a role in preventing or reversing coronary disease.[80][81] Vitamin D deficiency is associated with an increase in high blood pressure and cardiovascular risk. When researchers monitored the vitamin D levels, blood pressure and other cardiovascular risk factors of 1739 people, of an average age of 59 years for 5 years, they found that those people with low levels of vitamin D had a 62% higher risk of a cardiovascular event than those with normal vitamin D levels.[82] Low levels of vitamin D have also been implicated in hypertension, elevated VLDL triglycerides, and impaired insulin metabolism.[83]
A report from the National Health and Nutrition Examination Survey (NHANES) involving nearly 5,000 participants found that low levels of vitamin D were associated with an increased risk of peripheral artery disease (PAD). The incidence of PAD was 80% higher in participants with the lowest vitamin D levels (<17.8 ng/mL).[39] Cholesterol levels were found to be reduced in gardeners in the UK during the summer months.[84] Heart attacks peak in winter and decline in summer in temperate[85] but not tropical latitudes.[86]
The issue of vitamin D in heart health has not yet been settled. Exercise may account for some of the benefit attributed to vitamin D, since vitamin D levels are generally higher in physically active persons.[87] Moreover, there may be an upper limit after which cardiac benefits decline. One study found an elevated risk of ischaemic heart disease in Southern India in individuals whose vitamin D levels were above 89 ng/mL.[52] These sun-living groups results do not generalize to sun-deprived urban dwellers. Among a group with heavy sun exposure, taking supplemental vitamin D is unlikely to result in blood levels over the ideal range, while urban dwellers not taking supplemental vitamin D may fall under the levels recognized as ideal.
[edit]Role in all-cause mortality

Using information from the National Health and Nutrition Examination Survey a group of researchers concluded that having low levels of vitamin D (<17.8 ng/mL) was independently associated with an increase in all-cause mortality in the general population.[88] The study evaluated whether low serum vitamin D levels were associated all-cause mortality, cancer, and cardiovascular disease (CVD) mortality among 13,331 diverse American adults who were 20 years or older. Vitamin D levels of these participants were collected over a 6-year period (from 1988 through 1994), and individuals were passively followed for mortality through the year 2000.
Among many factors that may be responsible for vitamin D's apparent beneficial effect on all-cause mortality is its effect on telomeres and its potential effect on slowing aging. Shortening of leukocyte telomeres is a marker of aging. Leukocyte telomere length (LTL) predicts the development of aging-related disease, and length of these telomeres decreases with each cell division and with increased inflammation (more common in the elderly) Research indicates that vitamin D is a potent inhibitor of the proinflammatory response and slows the turnover of leukocytes. Higher vitamin D levels were also associated with longer leukocyte telomere length, indicating that vitamin D sufficiency may be play a role in preventing age-related diseases.[89]

Call my office to set up an appointment or email me 815-476-5210 or

Monday, October 5, 2009

TS Wiley Lecture at the AustrailAsian Academy of Anti-Aging Medicine

Sep 30, 2009 14:22 ET

SANTA BARBARA, CA--(Marketwire - September 30, 2009) -TS Wiley talked about menopause and andropause for both sexes along with the benefits of rhythmic, bioidentical hormone replacement therapy (BHRT) to a medical audience actively involved in anti-aging, preventive, regenerative and aesthetic medicine.

"Unfortunately, the current state of BHRT for menopausal women does not address the correct scientific template to affect real recovery," said T.S. Wiley, author and founder of the Wiley Protocol. "Creating a BHRT regimen that does not fully restore complete replacement values and menses seems as if it would further derange the template of hormonal and environmental interrelatedness that has evolved over millennia."

Wiley's approach to Bioidentical Hormone Replacement Therapy (BHRT) is rhythmic, or biomimetic hormone replacement for menopausal women who experience mood swings, foggy thinking, anxiety, night sweats, sleeplessness, depression and/or lack of libido. It employs plant derived hormones dosed in escalating and descending biomimetic curves.

The latest research on bioidentical hormone replacement therapy suggests that women must cycle their hormones and have a menstrual bleed to be truly safe from cardiovascular events. According to a recent Danish study on 700,000 women, a combined cyclic regimen of bioidenticals with monthly bleeding creates a lower cardiovascular risk for women than continuous-combined estrogen, progesterone, and progestin therapy, which does not provide menses. Current standards for BHRT are the same as synthetics -- statically dosed, continuous-combined, which does not intend to provide a menstrual period.

She continued, "Bearing this in mind, consider a new approach to BHRT, including a protocol which provides women with a more accurate form of restoration for lost endocrine function at the steroid receptor level as well as effecting the physiologic functional medicine approach. The components of this transdermal protocol and the amount of hormones women take vary throughout the female 28-day cycle to mimic the hormone levels of a woman in her prime."

T.S. Wiley is the developer of The Wiley Protocol® rhythmic, compounded bioidentical hormones, and has pioneered the standardization of the patent pending Wiley Protocol formulations using unique, standardized compounding procedures and color coded packaging, available to physicians and patients at recommended retail prices. The company's biomimetic hormone protocols must be formulated by a trained and registered compounding pharmacist.

Wiley Systems, Inc distributes the following biomimetic dosing schedules: The Wiley Protocol™ for Women; Wiley Protocol for Men™, biomimetic DHEA and testosterone restoration; Wiley Protocol Thyroid™ for Women, biomimetic thyroid hormone restoration; Wiley Protocol Testosterone™ for Women, biomimetic testosterone restoration; and Wiley Protocol Face Crème™, which promotes a more youthful appearance by filling in fine lines with the body's own adiposities.

T.S. Wiley is a medical theorist in environmental endocrinology and Darwinian medicine, and has residences in both Santa Fe, New Mexico and Santa Barbara, California. She is a noted writer, researcher and lecturer on the effects of hormones, particularly in menopausal women as well as an accepted expert in chronobiology and circadian rhythmicity. Wiley's environmental endocrinology seminars, "Two Days Back on Earth" in Glendale, California are attended by physicians from around the world.

About Wiley Systems, Inc. and the Wiley Protocol. The Wiley Systems, Inc. was founded in 2005 in Santa Barbara, California by T.S. Wiley, who is the developer of the Wiley Protocol®, a trademarked patent pending delivery system consisting of the biomimetic, bioidentical hormones estradiol and progesterone, or biomimetic hormone restoration therapy. Wiley Systems began as a project to fund the union of doctors and pharmacists in a common goal to standardize bioidentical hormones for academic research. Now in 2009, the Wiley Pharmacy Consortium numbers around 50 pharmacies and more than 250 doctors prescribing in the US and Canada.

The Wiley Protocol is only available at compounding pharmacies that have joined the project for future National Institutes of Health (NIH) study and have contractually agreed to the standardized methods, materials, packaging and recommended pricing. In exchange, Wiley Systems provides intellectual property and provides 28WP logo-bearing packaging consisting of color-coded bags and applicators. The Wiley Protocol name assures customers that they are receiving authentic Wiley Protocol dosing rhythms based on original research.